A very broad definition of depression has been defined as having a loss of pleasure in that which you had pleasure in before you got depressed. It’s interesting to note that depression can manifest like this but the deeper God question is what kind of pleasure are we seeking? Being depressed can come from seeking the pleasure you were made for without God. Lust is mostly centered around hoarding the God-given drive for what He has called good and fulfilling that drive in the wrong way.
The answer that takes some prayer and insight is that God is the only thing that satisfies, yet He does not take away the drives and passions we have. He gives us a choice to choose which pleasure will we fill ourselves with.
Depression can be a result of false pleasure in your life. “For the wages of sin is death, but the gift of God is eternal life.” In the Proverbs it says, “Hope deferred makes the heart sick, but desire fulfilled is a tree of life.”
Right hope in the right time produces life but you could say a false hope that is a broken cistern can produce “heart sickness” that we could call depression.
Over time we seek to bear fruit and that requires that we do all we can in God’s grace to get rid of anything that is killing the soil. Just the parable of the sower and the seeds alone shows us that three of the four recepients of the word don’t bear fruit(Mark 4). Removing hinderances I think will keep us aware of any form of depression that would try to hinder ‘desire fulfilled in God’ because this life is hard and full of sorrow at times but it is also an adventure to live. Fight with gratitude today!